What is the most well-considered philosophical stance on psychedelics?

Psychedelic drugs like dmt or psilocybin are serious drugs that are different from recreational drugs like weed, mushrooms or alcohol. There is a lot of research on their effect on the brain, physical body, their therapeutic applications etc, and many scientists, spiritual leaders, philosophers, people with extensive experience with psychedelics speak about their unique properties. <br><br>What is the philosophical stance on these drugs? What are the thoughts on how they work, their therapeutic effects, their spiritual nature, their nature in general? What do philosophers think about people who use psychedelics? <br><br>What are the philosophical applications of psychedelic use? <br><br>What are the thoughts on acid, dmt, psilocybin, mescaline, ayahuasca etc? What are the thoughts on microdosing, the therapeutic potential of psychedelic drugs and psychotherapy, it’s criminalization, the spiritual use of psychedelic drugs, the growth of psychedelic use in the modern world and the consequences of it?